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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS13C
All Species:
12.12
Human Site:
S475
Identified Species:
33.33
UniProt:
Q709C8
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q709C8
NP_001018098.1
3753
422390
S475
E
K
R
G
G
W
F
S
G
L
W
G
K
K
E
Chimpanzee
Pan troglodytes
XP_510458
3836
431033
S557
E
K
R
G
G
W
F
S
G
F
W
G
K
K
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851912
3629
408076
S475
E
K
R
G
G
W
F
S
G
F
W
G
K
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BX70
3748
420070
S474
G
E
K
R
G
W
F
S
G
F
W
G
K
K
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511058
3801
426177
G510
R
S
G
G
W
F
S
G
F
W
G
K
K
E
S
Chicken
Gallus gallus
XP_001233000
3758
422392
G477
K
S
G
G
W
F
S
G
F
W
G
R
R
E
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922767
3699
412330
F475
K
Q
S
G
G
G
F
F
S
S
F
F
G
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192977
2470
271032
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q07878
3144
357831
N132
I
L
S
T
Q
S
E
N
K
T
S
S
S
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.9
N.A.
87
N.A.
86.4
N.A.
N.A.
77.2
68.7
N.A.
59.6
N.A.
N.A.
N.A.
N.A.
24.1
Protein Similarity:
100
97.4
N.A.
92
N.A.
93.3
N.A.
N.A.
87.6
82.9
N.A.
76.8
N.A.
N.A.
N.A.
N.A.
41
P-Site Identity:
100
93.3
N.A.
93.3
N.A.
66.6
N.A.
N.A.
13.3
6.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
93.3
N.A.
93.3
N.A.
80
N.A.
N.A.
26.6
33.3
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
34
12
0
0
0
0
12
0
0
0
0
0
0
23
45
% E
% Phe:
0
0
0
0
0
23
56
12
23
34
12
12
0
0
0
% F
% Gly:
12
0
23
67
56
12
0
23
45
0
23
45
12
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
23
34
12
0
0
0
0
0
12
0
0
12
56
56
12
% K
% Leu:
0
12
0
0
0
0
0
0
0
12
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
12
0
0
12
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
12
0
34
12
0
0
0
0
0
0
0
12
12
0
0
% R
% Ser:
0
23
23
0
0
12
23
45
12
12
12
12
12
12
34
% S
% Thr:
0
0
0
12
0
0
0
0
0
12
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
23
45
0
0
0
23
45
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _